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Strontium Support II - 341 mg per vegi-cap - 120 vegi-caps - AOR (08204)
Strontium Support II - 341 mg per vegi-cap - 120 vegi-caps - AOR (08204) Quantity in Basket: None
Code: AOR-SS120


Price: $27.97

Quantity:  

Strontium Support II from AOR
 
Supports Skeletal Health*
Dosage:  341 mg
Size: 120 vegi-caps
Category: AOR
  Product Number: 08204
Product Code: AOR-SS120

.

Strontium Support is an organic, stable strontium form (not to be confused with the radioactive strontium-90 isotope). Strontium is a trace mineral in the diet whose metabolism is closely tied to that of calcium, and which concentrates in the skeletal system, where it supports the function of osteoblasts (the cells which form new bone) while reducing the differentiation and activity of osteoclasts (the cells which resorb old bone). Extensive evidence supports a role for strontium in supporting skeletal health.

Product Discussion from AOR:

Strontium: The First Bone-Building Supplement!

Bone loss accelerates suddenly in menopausal women because the drop in estrogen levels causes an increase in the resorption (teardown) of existing bone. But resorption is only half of the story. Age-related bone loss is also caused by a decrease in the formation of new bone tissue.

Existing drugs for treating osteoporosis, as well as calcium and vitamin D supplements, work by reducing bone resorption. But they do not support the formation of new bone. These drugs and nutrients increase the mineralization of bone, but they do not help the body to build new bone tissue. And in fact, within weeks of starting use of antiresorptive drugs like Fosamax,® the body’s formation of new bone actually decreases. The resulting bone is less prone to fracture, but is not the same as youthful, healthy bone.

Strontium is a mineral found along with calcium in most foods. Research has long suggested that it may be an essential nutrient required for the normal development, structure, function, and health of the skeletal system. Clinical trials going back into the 1940s have supported this conclusion, but recent studies have provided evidence that it can offer unique nutritional support against loss of bone structure and function.

Animal studies have shown that Strontium supplements both decrease bone resorption, and increase the formation of new bone tissue.
• In animal models, Strontium (in various forms, such as chloride, carbonate, gluconate, and lactate) causes “baby” osteoblasts (bone-building cells) to multiply more quickly.
• Bone tissue cultures which are exposed to Strontium synthesize more bone matrix and new bone collagen. The same amount of calcium has no effect on these parameters.
• In bone tissue culture, Strontium reduces bone resorption at concentrations at which calcium has no effect, prevents the resorption caused by excessive parathyroid hormone, and slows the rate at which immature osteoclasts develop.
• Strontium-supplemented diets boost bone strength in experimental animals without a negative impact on bone quality, even at extremely high doses.

Human clinical trials also support Strontium’s ability to both support new bone formation and prevent excessive resorption.
• The results of early clinical trials using Strontium (lactate) led researchers to speculate that Strontium increased osteoblast activity.
• Bone biopsies from a small human pilot trial revealed an astounding 172.4% increase in new bone formation after six months of Strontium (gluconate) supplementation.
• The bone-building activity of osteoblasts can be measured using bone-specific alkaline phosphatase, while crosslinked N-telopeptide (NTx) and C-telopeptide (CTx) mark the degradation of bone collagen by ravaging osteoclasts.

Unlike the range of side-effects that accompany antiresorptive drugs, no clinical side-effects have ever been reported that could be clearly attributed to Strontium.

Calcium and Strontium: the Dynamic Tension

Calcium and Strontium can both play key roles in the health of your bones – if you use them properly. On the one hand, animal studies suggest that Strontium is not effective, and may even be counterproductive, if your calcium intake is not adequate. Current “official” recommendations suggest an intake of 1000 milligrams of calcium for younger adults, and 1200 milligrams for people over the age of 50. Some evidence suggests that a still higher intake (1300-1600 milligrams) of calcium is more effective for lowering fracture risk in the elderly. But remember that these numbers are your total calcium need. The more calcium you get in your diet, the less you need from supplements.

At the same time, however, it’s important not to take your Strontium supplement at the same time as your calcium supplements. This is because calcium and Strontium use the same pathways for absorption in the intestinal tract, so that swallowing a calcium supplement along with your Strontium can dramatically reduce absorption. So obviously, putting Strontium and calcium in the same pill is a recipe for bone health disaster, in which you don’t get the benefits of either nutrient!

The best protocol – and the one used in the most recent clinical trials – is to take your Strontium either three hours after your last meal of the day, or one hour before breakfast in the morning, or both. Because studies suggest that one last dose of calcium just before retiring can help prevent excessive resorption of bone overnight, it may be best to take all of your Strontium before breakfast, leaving you free to take a calcium supplement just before you go to bed.

Like the Strontium carbonate crystals (strontianite) from which it was first isolated, Strontium’s role in bone health has long been hidden in obscurity. But its strength has allowed it to endure, waiting for the day that it could emerge and reveal its power.

References

1 Sips, AJAM et-al. Intestinal absorption of strontium chloride in healthy volunteers: pharmacokinetics and reproducibility.Br. J Clin Pharmacol. 1996;41:543-549

2 Sips, AJAM.Absoption kinetics of strontium and calcium in human and experimental animal. Ph.D Thesis. University of Amsterdam. 1994

3 Skoryna, SC. Effects of oral supplementation with stable strontium. Can Med J. 1981;125:703-712

4 ATSDR.Toxicological profile for strontium. Atlanta,GA: Agency for toxic substances and disease registry US Dept of Health and Human Services. Public Health Services.2001

5 Leeuwenkamp,OR et-al. Human pharmacokinetics of orally administered strontium. Calcif. Tissue Int. 1990;47:136-140

6 Marie,PJ et-al. Effect of low doses of stable strontium on bone metabolism in rats. Mineral Electrolyte Metab. 1985;11:5-13

7 Shorr, E and Carter, AC. The value of strontium as an adjuvant to calcium in the mineralization of the skeleton in osteoporosis in man. Conference on Metabolic Interactions. Eds. EC Reifenstein Jr.,NY.NY.Pub J Macy Foundation 1950 pp144-154.

8 McCaslin FE and Janes, HM. The effect of strontium lactate in the treatment of osteoporosis. Proc. Mayo Clinic. 1959;34:329-334

9 Skoryna,SC and Fuskova, M. In: Skoryna, SC ed. Handbook of stable strontium.NY;Plenum:1985.p593-617

10 Comar,CL , Wasserman, RH and Nold, NM. Strontium-Calcium discrimination factors in the rat. Proc. Sco. Exp. Biol. Med.1950;92:859-863

11 Della Rossa et-al. Absorption and retention of ingested strontium and calcium in beagles as a function of age. Nature.1965;205:197-198

12 Skoryna, SC.Metabolic aspects of the pharmacologic uses of trace elements in human subjects with specific references to stable strontium. Trace Subst. Enviorn Health.1984;18:3-23

13 Dahl, SG et-al. Incorporation and distribution of strontium in bone. Bone.2001;28:446-453

14 Storey,E. Strontium “rickets” bone calcium and strontium changes. Austral.Ann. Med. 1961;10:213-222

15 Matsumoto, A. Effect of strontium chloride on bone resorption induced by prostaglandin E2 in cultured bone. Arch. Toxicol. 1988;62:240-241

16 Marie,PJ et-al. Mechanisms of action and therapeutic potential of strontium in bone. Calcif. Tissue Int.2001;69:121-129.
The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes. Any reproduction in whole or part and in print or electronic form without express permission is strictly forbidden. Permission to reproduce selected material may be granted by contacting AOR Inc.
 

Suggested Usage: Take one to three capsules daily on an empty stomach, one hour before breakfast and/or three hours after the last meal of the day, or as directed by a qualified health consultant.

Other Label Information:  Keep out of reach of children.  Ensure calcium intake is also adequate. Do not take at the same time as calcium supplements.  Avoid if pregnant or nursing.
 

SUPPLEMENT FACTS
Serving Size: 1 capsule
 
  Amount  % DV

Strontium (from citrate) 341 mg *

*Daily Value not established

Contains no common allergen.

Vegetarian Capsule consists of hypromellose, sorbitol, silicon dioxide, water.
 
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.